Metastatic prostate carcinoma

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  I low-power view of the FNA smears contained numerous round or oval abnormal cells (Pap stain).
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  II Large tumor cells of metastatic prostate adenocarcinoma in FNA smears of the lymph node
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  Tumor cells arranged single and in papillary clusters
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  Aggregate of malignant cells with marked nuclear enlargement.
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  Tumor cells in a papillary group with round enlarged nuclei.
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  Tumor cells in a papillary group with vacuolated cytoplasm.
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  Adenocarcinoma-like cluster of large malignant cells with large nuclei and macronucleoli.
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  Pleomorphic malignant cells with hyperchromatic eccentric nuclei and dense cytoplasm.
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  Cytoplasm in rather pale and ill- defined in some tumor cells
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  Aggregate of malignant cells with indistinct cell borders.
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  The hyperchromatic nuclei were round or oval but varied greatly in size.
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  Tumor cells with nuclear outline irregular.
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  Cluster of tumor cells with prominent nucleoli.

Adencoarcinoma of the prostate is by for the most common malignacy of the prostate and one of the leading causes of cáncer-related death in males.
Metastasis to the regional lymph nodes occurs frequently and indicates a poorer prognosis compared with patients without lymph node metastasis.
The images correspond to the FNA cytology of the inguinal lymph node that was performed in a patient of 74 years of age.
The FNA smears contained abundant tumor cells lying single or in aggregates. The cells varied widely in size and shape, the nuclei were round or oval, and the nucleoli were prominent and sometimes irregular in shape.
These morphologic features were interpreted as consistent with adenocarcinoma.