Gynecologic cytology

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  Normal superficial and intermédiate squamous cells desquamed from nonkeratinizing squamous epithelium.
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  Superficial squamous cells in a cervical smear with abundant translucent cytoplasm and pyknotic nuclei.
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  Estrogenic effects are manifested by the appearance of large falt dissociated eosinophilic superficial squamous cells in a clean background.
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  Intermediate cells in cervical smear.
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  Parabasal cells. Round to oval cells with relatively large nuclei an scant dense, cyanophilic cytoplasm.
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  Placa de células parabasales en una muestra atrófica. El Plaque of parabasal cells in an atrophic sample. The cytoplasm of some cells has degenerated presenting some free nuclei in the extended.
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  Cervical smear taken after menopause with evidence of inflamation degenerative nuclear changes and drying artifacts.
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  Smear from an atrophic cervix composed enterely of parabasal cells showing degenerative changes. There are numerous leucocytes and mucous strands.
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  Sheet of columnar cells. Sharply outlined cytoplasmic boundaries create a honey comb pattern.
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  Endocervical cells with poblet cell morphology due to distensión with mucin.
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  Bare nuclei are frequently seen around endocervical cell groups.
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  Endocervical columnar cells, which have terminal bars and cilia.
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  Endocervical ciliated cells.
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  Cytolisis. Bare nuclei are due to lysis of the cytoplasm. Döderlein bacilli are conspicuous.
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  Numerous Döderlein bacilli in a cytolytic smear with intermédiate cells an free nuclei.
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  Background mucus stained pole pink o green is a useful indicator of sampling from the cervix.
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  The mucous plug contains inflammatory cells but the remainder of the smear will be clean.
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  Anucleated squames desquemated from the superficial layers of keratinized-hyperkeratotic- squamous epithelium.
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  A good-quality sample consists of well-displayered cells with representative sampling of both squamous and endocervical or metaplastic epithelium.
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  Squamous cells and tall columnar cells with eccentricelly located nuclei and abundant cytoplasm.
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  Unsatisfactory sample due to an excess of polymorphs in a conventional smear.
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  Unsatisfactory sample due to an excess of blood in a conventional smear.
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  Inmature squamous metaplasie showing spiderly cytoplasmic projections due to forceful removal of the cells from the mucosa.
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  A metaplastic group showing angular and polygonal cells with dense blue-green cytoplasm and nuclei resembling those of endocervical cells.
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  Inmature squamous metaplasia cells liying sinply and in a sheet with relatively large nuclei indistint cell corders and homogeneous or fine vacuolated cytoplasm.
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  Inmature squamous metaplasia cell with a high nucleocytoplasmic ratio. Large nuclei with a finely granular chromatin.
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  Slightly atyplical relatively mature squamous metaplastic cells with slightly irregular some whot enlarged nuclei.
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  Immature squamous metaplasia cells liying simple and in a sheet.
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  Smear pattern in non-specific cervicitis with numerous polymorphs.
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  An endometrial cell ball.
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  Degenerate endometrial cells are darkly stained. Cell detail are difficult to see.
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  Multinucleated macrophages or giant cells are non-specific finding especially after the menopause.
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  Colonies de actinomices. Numerous filamentous structures radiating from the center.
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  Actinomyces organisms presenting in colonies of filamentous organisms with no significant inflammation.
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  Budding yeasts and pseudohyphae of Candida Albicans in a lightly inflamed cervical smear.
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  Candida Albicans. Long eosinophilic septate filaments and budding yeasts.
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  Candida hyphae forming a tangled mass overlying a plaque of squamous cells. Some spores between the hyphae.
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  Coccoid overgrowth creating a bacterial hare over superficial cells.
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  Normal plygonal squamous cells having there transparent cytoplasm covered by tiny coccobacillary forms of Gardnerella Vaginalis.
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  Trichomonas vaginalis organisms are rounded or ovoid cyanophilic organisms.
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  Tricomonas adheridas a la superficie de células escamosas.
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  Perinuclear halo in a superficial cell forming a narrow zone of pallor around the nucleus. This is a non- specific inflammatory response most often seen in Trichomonas vaginalis infection.
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  Bizarre cells in a smear with Herpes genitalis infectión.
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  Herpes Simplex Virus changes in cervical epithelial cells.
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  Bizarre cells in a smear with Herpes genitalis infectión.
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  Initielly there is swelling of the nuclei followed by degeneration of chromatin leading to a ground glass pattern.
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  Herpes Genitalis infection. Multinucleation is a prominent feature.
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  Koilocytes with well-defined clearing of cytoplasm around the nuclei and variable nuclear enlargement.
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  Condylomatous change in mature squamous epithelium. Irregularity in nuclear size and shape and conspicuous nuclear halos.
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  Koilocytes showing bordeline nuclear changes in which. The nuclei appear near normal with minimal enlargement and change in chromatin.
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  Koilocytotic cells. Large perinuclear halo. Dense outer zone of the cytolplasm an enlarged nucleus with dense hyperchromatic nuclear chromatin.
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  Human Papillomavirus (HPV) Infection. Celular clumping or plaque formation commonly observed in this infection.
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  Koilocytotic atypia. Cervical smears with LSIL showing cells with vacuolization of the cytoplasm and slight atypia of the nuclei.
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  HPV infection low grade squamous intraepithelial neoplasm LSIL changes.
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  L-SIL. Cells of squamous type with slightly enlarged nuclei and some hyperchromasia.
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  Cells of squamous type with slightly enlarged nuclei. The nuclear chromatin is finely granular and very slightly.
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  L-SIL. Patrón cromatínico anormal con irregularidades en los contornos nucleares agrandamiento nuclear e hipercromasia. Las células tienen abundante citoplasma.
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  L-SIL. The cells show varing nuclear enlargement abundant chromatin pattern mild irregularities of outline.
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  L-SIL. Nuclear enlargement and abnormal chromatin pattern. The cytoplasmic clearing probably indicate HPV infection.
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  HPV infection low grade squamous intraepithelial neoplasm LSIL changes.
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  H-SIL. Cells very in size and shape. Nuclei are round to oval and irregular in shape. Nuclear chromatin is in part finely, in part coarsely granular and moderately hyperchromatic. Incrased nucleocytoplasmic ratio.
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  H-SIL. Los núcleos muestran variable hipercromasia patrón cromatínico anormal e irregularidades en el contorno nuclear.
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  H-SIL. The nuclei of the cells are hyperchromatic have irregular outlines and show complex folding.
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  H-SIL. Cells and nuclei are irregularly shaped. granular and coarse hyperchromatic nuclear chromatin.
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  Cells very in size and shape. Nuclei are round to oval and irregular in shape. Nuclear chromatin is coarsely granular and hyperchromatic. Incrased nucleocytoplasmic ratio.
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  Squamous Carcinoma. Clusters of small dark cancer cells blood and debris.
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  Squamous Carcinoma. The smear contained more cells in which the grossly abnormal nuclei are associated with crenated borders and margination of the chromatin.
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  Squamous Carcinoma. A large number of severely abnormal cells together with inflamatory cells.
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  Squamous Carcinoma. Disproportionate enlargement of the nucleus, increased chromatin content and hyperchomasia.
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  Squamous Carcinoma.The nuclei vary in shape and size and present abnormal chromatin pattern
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  Squamous Carcinoma. These cells show disproporcionate enlargement of the nucleus, increased chromatin and hyprechomasia.
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  Squamous Carcinoma. Hyperchromasia and pleomorphism are the striking features. Irregular distribution of the coarsely clumped chromatin.
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  Endocervical Adenocarcinoma. A cluster with smooth rounded borders and secretory vacuoles.
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  Endocervical Adenocarcinoma. These cells contain secretory vacuoles and form rounded clusters with smooth outlines.
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  Endocervical adenocarcinoma. Cellular accumulation with nuclear degeneration.
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  Endocervical Adenocarcinoma.Papillary cluster of large elongated cancer cells with hyperchomatic and enlarged nuclei.
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  Endocervical Adenocarcinoma. Endocervical cell atypia. The cells show considerable variability of cell sizes.
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  Endocervical Adenocarcinoma. A cluster of endocervical cells with marked atypia.
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  Endocervical Adenocarcinoma. Undifferentiated cancer cells. Note the absence of any distinguishing cytoplasmic features. The nuclei are markedly abnormal and hyperchomatic.
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  Poorly-differentiated endocervical adenocarcinoma. Cells with hypercromatic nuclei closely resemble poorly-differentiated malignant squamous cells.

Invasive squamous cell carcinoma of the cérvix is antedated by precancerous changes in the cervical epithelium, which can be identified cytologicaly. The abnormal cells exfoliated from the cervix gave rise to the use of the cervical smear test for the detection of intraepithelial neoplastic change. The probability of successful treatment of precancerous changes wake the discase process and ideal target for population screening.